Defining intermediate stages in cell determination: acquisition of a lens-forming bias in head ectoderm during lens determination.

@article{Grainger1997DefiningIS,
  title={Defining intermediate stages in cell determination: acquisition of a lens-forming bias in head ectoderm during lens determination.},
  author={Robert M. Grainger and Joe Mannion and Tara L Cook and C A Zygar},
  journal={Developmental genetics},
  year={1997},
  volume={20 3},
  pages={246-57}
}
Cell determination in vertebrates requires integration of many events, although the mechanisms controlling the different stages in this process are poorly understood. While studies of lens determination have helped define some of these stages, we know very little about the intermediate steps involved in the commitment of ectoderm to lens formation. Lens determination begins during gastrulation when ectoderm is briefly competent to respond to lens-inducing signals and progresses to a point, at… CONTINUE READING

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