Defining functional signatures of dysbiosis in periodontitis progression

Abstract

Periodontitis is a common inflammatory disease that leads to tooth loss and has been linked to cardiovascular disease and diabetes mellitus. The periodontal microbiome is highly diverse, and metatranscriptomic studies have indicated that the genes that are expressed by the microbiota are more relevant than the microbial composition in the pathogenesis of… (More)
DOI: 10.1186/s13073-015-0165-z

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