Defining clinico-neuropathological subtypes of mesial temporal lobe epilepsy with hippocampal sclerosis.

@article{Blmcke2012DefiningCS,
  title={Defining clinico-neuropathological subtypes of mesial temporal lobe epilepsy with hippocampal sclerosis.},
  author={Ingmar Bl{\"u}mcke and Roland Coras and Hajime Miyata and Ciğdem Ozkara},
  journal={Brain pathology},
  year={2012},
  volume={22 3},
  pages={402-11}
}
Hippocampal sclerosis (HS) is the most frequent cause of drug-resistant focal epilepsies (ie, mesial temporal lobe epilepsy with hippocampal sclerosis; mTLE-HS), and presents a broad spectrum of electroclinical, structural and molecular pathology patterns. Many patients become drug resistant during the course of the disease, and surgical treatment was proven helpful to achieve seizure control. Hence, up to 40% of patients suffer from early or late surgical failures. Different patterns of… CONTINUE READING
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