Defining a neuron: neuronal ELAV proteins

  title={Defining a neuron: neuronal ELAV proteins},
  author={Alessia Pascale and Marialaura Amadio and Alessandro Quattrone},
  journal={Cellular and Molecular Life Sciences},
Neuronal cells strongly depend on the control exerted by RNA-binding proteins (RBPs) on gene expression for the establishment and maintenance of their phenotype. Neuronal ELAV (nELAV) proteins are RBPs able to influence virtually every aspect of the postsynthesis fate of bound mRNAs, from polyadenylation, alternative splicing and nuclear export to cytoplasmic localization, stability and translation. They enhance gene expression through the last two, best documented activities, increasing mRNA… CONTINUE READING
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