Defining a molecular atlas of the hippocampus using DNA microarrays and high-throughput in situ hybridization.

@article{Lein2004DefiningAM,
  title={Defining a molecular atlas of the hippocampus using DNA microarrays and high-throughput in situ hybridization.},
  author={Ed S Lein and Xinyu Zhao and Fred H. Gage},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2004},
  volume={24 15},
  pages={3879-89}
}
The hippocampus consists of a series of cytoarchitecturally discrete subregions that can be distinguished from one another on the basis of morphology, connectivity, and electrophysiological properties. To understand the molecular underpinnings for these differences, DNA microarrays were used to find genes predicted to be enriched in subregions CA1, CA3, and the dentate gyrus, and >100 of these genes were subsequently analyzed using in situ hybridization to obtain cellular-level localization of… CONTINUE READING
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