Defined patterns of neuronal networks on 3D thiol-functionalized microstructures.

Abstract

It is very challenging to study the behavior of neuronal cells in a network due to the multiple connections between the cells. Our idea is then to simplify such a network with a configuration where cells can have just a fixed number of connections in order to create a well-defined and ordered network. Here, we report about guiding primary cortical neurons with three-dimensional gold microspines selectively functionalized with an amino-terminated molecule.

DOI: 10.1021/nl502922b

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Cite this paper

@article{Santoro2014DefinedPO, title={Defined patterns of neuronal networks on 3D thiol-functionalized microstructures.}, author={F. Santoro and Gregory Panaitov and Andreas Offenh{\"a}usser}, journal={Nano letters}, year={2014}, volume={14 12}, pages={6906-9} }