Deficits in social behavior and reversal learning are more prevalent in male offspring of VIP deficient female mice

@article{Stack2008DeficitsIS,
  title={Deficits in social behavior and reversal learning are more prevalent in male offspring of VIP deficient female mice},
  author={Conor M. Stack and Maria A. Lim and Katrina Cuasay and Madeleine M. Stone and Joanna M. Hill},
  journal={Experimental Neurology},
  year={2008},
  volume={211},
  pages={67-84}
}
  • Conor M. Stack, Maria A. Lim, +2 authors Joanna M. Hill
  • Published in Experimental Neurology 2008
  • Medicine, Biology
  • Blockage of vasoactive intestinal peptide (VIP) receptors during early embryogenesis in the mouse has been shown to result in developmental delays in neonates, and social behavior deficits selectively in adult male offspring. Offspring of VIP deficient mothers (VIP +/-) also exhibited developmental delays, and reductions in maternal affiliation and play behavior. In the current study, comparisons among the offspring of VIP deficient mothers (VIP +/-) mated to VIP +/- males with the offspring of… CONTINUE READING

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