Deficits in cortico-striatal synaptic plasticity and behavioral habituation in rats with portacaval anastomosis.

@article{Sergeeva2005DeficitsIC,
  title={Deficits in cortico-striatal synaptic plasticity and behavioral habituation in rats with portacaval anastomosis.},
  author={Olga A. Sergeeva and Daniela Schulz and Nana Doreulee and Alexei A. Ponomarenko and Oliver Selbach and Elena Borsch and Gerald Kircheis and Joseph P. Huston and Dieter H{\"a}ussinger and Helmut L. Haas},
  journal={Neuroscience},
  year={2005},
  volume={134 4},
  pages={1091-8}
}
Hepatic encephalopathy is characterized by disturbances of motor and cognitive functions involving the basal ganglia. So far no standards for assessment of neuropsychiatric abnormalities (disorders of sleep, mood, anxiety and personality) in subclinical hepatic encephalopathy have been defined. Using an animal model of mild (subclinical) hepatic encephalopathy we investigated now striatum-related behaviors and cortico-striatal synaptic plasticity in rats 2 months after introduction of a… CONTINUE READING

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