Deficient activity of stimulatory nucleotide-binding regulatory protein in lymphocytes from patients with essential hypertension.

Abstract

Lymphocytes are widely used as a model for the cardiovascular beta-adrenoceptor-adenylate cyclase system. We evaluated the role of this system in the pathogenesis of hypertension by studying lymphocytes obtained from patients with essential hypertension. Untreated hypertensive patients and normotensive control subjects were studied. The number and affinity… (More)

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@article{Yoshikawa1994DeficientAO, title={Deficient activity of stimulatory nucleotide-binding regulatory protein in lymphocytes from patients with essential hypertension.}, author={H. Yoshikawa and K. Fukuda and Y Wanaka and Keiko Kasamatsu and Akemi Baba and Isuta Nishio and Yukiko Masuyama}, journal={American journal of hypertension}, year={1994}, volume={7 8}, pages={713-6} }