Deficiency of density-dependent regulation of cell growth in the culture of skin fibroblasts from patients with mucolipidosis III.

Abstract

Cultured skin fibroblast cells were prepared from two patients with mucolipidosis III (ML III), which is a genetic disorder characterized by low activities of multiple lysosomal enzymes in fibroblasts. Genetic complementation analysis of fused fibroblast hybrids revealed that the patients were classified in different complementation groups. Growth curves of… (More)

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@article{Oohira1987DeficiencyOD, title={Deficiency of density-dependent regulation of cell growth in the culture of skin fibroblasts from patients with mucolipidosis III.}, author={Atsuhiko Oohira and Fumiko Matsui and Takashi Oki and Hirotaka Nogami}, journal={Journal of cell science}, year={1987}, volume={87 ( Pt 2)}, pages={249-57} }