Deficiency of cartilage oligomeric matrix protein causes dilated cardiomyopathy

@article{Huang2013DeficiencyOC,
  title={Deficiency of cartilage oligomeric matrix protein causes dilated cardiomyopathy},
  author={Yaqian Huang and Jiahong Xia and Jingang Zheng and Bin Geng and Peng Liu and Fang Yu and Bo Yang Victor Liu and Hongquan Zhang and Mingjiang Xu and Ping Ye and Yi Zhu and Qingbo Xu and Xian Wang and Wei Kong},
  journal={Basic Research in Cardiology},
  year={2013},
  volume={108},
  pages={1-21}
}
Alterations in cardiac extracellular matrix are involved in dilated cardiomyopathy (DCM) and its progression to heart failure. The matricellular protein cartilage oligomeric matrix protein (COMP) has been indicated localized in the heart. However, the role of COMP in cardiac homeostasis and disease remains elusive. COMP −/− mice, both male and female… CONTINUE READING