Deficiency of P-selectin or P-selectin glycoprotein ligand-1 leads to accelerated development of glomerulonephritis and increased expression of CC chemokine ligand 2 in lupus-prone mice.

@article{He2006DeficiencyOP,
  title={Deficiency of P-selectin or P-selectin glycoprotein ligand-1 leads to accelerated development of glomerulonephritis and increased expression of CC chemokine ligand 2 in lupus-prone mice.},
  author={Xiaodong He and Trenton R. Schoeb and Angela Panoskaltsis-Mortari and Kurt R. Zinn and Robert A Kesterson and Junxuan Zhang and Sharon L. Samuel and Martin J. Hicks and Michael J Hickey and Daniel C. Bullard},
  journal={Journal of immunology},
  year={2006},
  volume={177 12},
  pages={8748-56}
}
The selectins and their ligands mediate leukocyte rolling on endothelial cells, the initial step in the emigration cascade leading to leukocyte infiltration of tissue. These adhesion molecules have been shown to be key promoters of acute leukocyte emigration events; however, their roles in the development of long-term inflammatory responses, including those that occur during chronic inflammatory diseases such as systemic lupus erythematosus, are unclear. To assess participation of P-selectin in… CONTINUE READING
16 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Similar Papers

Loading similar papers…