Deficiency in trefoil factor 1 (TFF1) increases tumorigenicity of human breast cancer cells and mammary tumor development in TFF1-knockout mice

@inproceedings{Buache2011DeficiencyIT,
  title={Deficiency in trefoil factor 1 (TFF1) increases tumorigenicity of human breast cancer cells and mammary tumor development in TFF1-knockout mice},
  author={Emilie Buache and Nicolas Etique and Fabien Alpy and I Stoll and M Muckensturm and Bernardo Reina-San-Martin and Marie Pierre Chenard and Catherine Tomasetto and Marl{\`e}ene Rio},
  booktitle={Oncogene},
  year={2011}
}
Although trefoil factor 1 (TFF1; previously named pS2) is abnormally expressed in about 50% of human breast tumors, its physiopathological role in this disease has been poorly studied. Moreover, controversial data have been reported. TFF1 function in the mammary gland therefore needs to be clarified. In this study, using retroviral vectors, we performed TFF1 gain- or loss-of-function experiments in four human mammary epithelial cell lines: normal immortalized TFF1-negative MCF10A, malignant… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 58 REFERENCES

Are trefoil factors oncogenic?

VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Trefoil factors in human milk.

VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Tissue Localization of Human Trefoil Factors 1, 2, and 3

  • The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
  • 2007
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

High expression of the trefoil protein TFF1 in interval breast cancers.

  • The American journal of pathology
  • 2001
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL