Deficiency in the omega-3 fatty acid pathway results in failure of acrosome biogenesis in mice.

Abstract

An omega-3 fatty acid, docosahexaenoic acid (DHA), is enriched in testicular membrane phospholipids, but its function is not well understood. The Fads2 gene encodes an enzyme required for the endogenous synthesis of DHA. Using Fads2-null mice (Fads2-/-), we found in our preceding studies that DHA deficiency caused the arrest of spermiogenesis and male… (More)
DOI: 10.1095/biolreprod.110.089524

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Cite this paper

@article{RoquetaRivera2011DeficiencyIT, title={Deficiency in the omega-3 fatty acid pathway results in failure of acrosome biogenesis in mice.}, author={Manuel Roqueta-Rivera and Timothy L Abbott and Mayandi Sivaguru and Rex Allen Hess and Manabu T. Nakamura}, journal={Biology of reproduction}, year={2011}, volume={85 4}, pages={721-32} }