Deficiencies of myocardial troponin-T and creatine kinase MB isoenzyme in dogs with idiopathic dilated cardiomyopathy.

@article{OBrien1997DeficienciesOM,
  title={Deficiencies of myocardial troponin-T and creatine kinase MB isoenzyme in dogs with idiopathic dilated cardiomyopathy.},
  author={P. A. O'Brien},
  journal={American journal of veterinary research},
  year={1997},
  volume={58 1},
  pages={11-6}
}
  • P.A. O'Brien
  • Published 1997 in American journal of veterinary research
OBJECTIVE To test the hypothesis that the derangement of myocardial energy homeostasis characteristic of idiopathic dilated cardiomyopathy (IDCM) of Doberman Pinschers was attributable to deficiency of creatine kinase (CK) isoenzyme MB relative to CK isoenzyme MM and troponin-T (Tn-T). ANIMALS 9 Doberman Pinschers with advanced congestive heart failure attributable to IDCM and 9 mixed-breed dogs without cardiac disease (controls). PROCEDURE Myocardial myofibrillar CK-MM, mitochondrial CK… CONTINUE READING

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