Deferasirox pharmacokinetic and toxicity correlation in β-thalassaemia major treatment.

@article{Allegra2016DeferasiroxPA,
  title={Deferasirox pharmacokinetic and toxicity correlation in β-thalassaemia major treatment.},
  author={Sarah Allegra and Silvia De Francia and Jessica Cusato and Elisa Pirro and Davide Massano and Antonio Morales Piga and Antonio D'Avolio},
  journal={The Journal of pharmacy and pharmacology},
  year={2016},
  volume={68 11},
  pages={1417-1421}
}
OBJECTIVES Deferasirox adverse effects include the following: gastrointestinal disturbance, mild elevations in serum creatinine levels and intermittent proteinuria; these events are dose-dependent and reversible with drug discontinuation, but this solution can lead to an inadequate iron chelation. For these reasons, interindividual variability of drug… CONTINUE READING