Defensins in innate immunity

  title={Defensins in innate immunity},
  author={L. Hazlett and M. Wu},
  journal={Cell and Tissue Research},
  • L. Hazlett, M. Wu
  • Published 2010
  • Biology, Medicine
  • Cell and Tissue Research
  • The innate immune system is the first line of defense against many common microorganisms, which can initiate adaptive immune responses to provide increased protection against subsequent re-infection by the same pathogen. As a major family of antimicrobial peptides, defensins are widely expressed in a variety of epithelial cells and sometimes in leukocytes, playing an important role in the innate immune system due to their antimicrobial, chemotactic and regulatory activities. This review… CONTINUE READING
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