Defensins and cathelicidins: neutrophil peptides with roles in inflammation, hyperlipidemia and atherosclerosis.

@article{Kougias2005DefensinsAC,
  title={Defensins and cathelicidins: neutrophil peptides with roles in inflammation, hyperlipidemia and atherosclerosis.},
  author={Panagiotis G Kougias and Hong Chai and Peter H Lin and Q. -S. Yao and Alan B. Lumsden and Changyi Johnny Chen},
  journal={Journal of cellular and molecular medicine},
  year={2005},
  volume={9 1},
  pages={3-10}
}
Atherosclerosis is a disease that begins in fetal life and represents a leading cause of morbidity and mortality associated with significant socioeconomic consequences. A central concept with regard to its pathogenesis is that of endothelial cell dysfunction, which is associated with the release of a large number of mediators secreted by leukocytes that are present in large numbers at the sites of atheroma formation. Neutrophil peptides defensins and cathelicidins are essential elements of the… CONTINUE READING

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