Defensins: antimicrobial peptides of innate immunity

@article{Ganz2003DefensinsAP,
  title={Defensins: antimicrobial peptides of innate immunity},
  author={Tomas Ganz},
  journal={Nature Reviews Immunology},
  year={2003},
  volume={3},
  pages={710-720}
}
Key PointsWhat are defensins? What are the structural characteristics of the three vertebrate defensin subclasses?Which tissues and cells contain abundant defensins?How are defensins synthesized and processed?How is the synthesis and release of defensins regulated?What are the effects of defensins on biological membranes and on microorganisms?How do bacteria respond to limit the damage by defensins?What are the biological functions of defensins in innate immunity?AbstractThe production of… CONTINUE READING

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