Defending the zygote: search for the ancestral animal block to polyspermy.

  title={Defending the zygote: search for the ancestral animal block to polyspermy.},
  author={Julian L. Wong and Gary M Wessel},
  journal={Current topics in developmental biology},
Fertilization is the union of a single sperm and an egg, an event that results in a diploid embryo. Animals use many mechanisms to achieve this ratio; the most prevalent involves physically blocking the fusion of subsequent sperm. Selective pressures to maintain monospermy have resulted in an elaboration of diverse egg and sperm structures. The processes employed for monospermy are as diverse as the animals that result from this process. Yet, the fundamental molecular requirements for… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 663 references

Proteolysis of Xenopus laevis egg envelope ZPA triggers envelope hardening.

Biochemical and biophysical research communications • 2004
View 12 Excerpts
Highly Influenced

Reduced fertility in male mice deficient in the zinc metallopeptidase NL1.

Molecular and cellular biology • 2004
View 5 Excerpts
Highly Influenced

The ecological and evolutionary

J. A. RiVell, P. J. Krug, R. K. Zimmer
View 6 Excerpts
Highly Influenced


X. Z. Xu, P. W. Sternberg
elegans sperm TRP protein required for sperm–egg interactions during fertilization. Cell 114, 285–297. • 2003
View 5 Excerpts
Highly Influenced

Developmental gene regulatory network architecture across 500 million years of echinoderm evolution.

Proceedings of the National Academy of Sciences of the United States of America • 2003
View 4 Excerpts
Highly Influenced

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