Defending the mitochondria: The pathways of mitophagy and mitochondrial-derived vesicles.

@article{Roberts2016DefendingTM,
  title={Defending the mitochondria: The pathways of mitophagy and mitochondrial-derived vesicles.},
  author={Rosalind F. Roberts and Matthew Y. Tang and Edward A. Fon and Thomas M. Durcan},
  journal={The international journal of biochemistry & cell biology},
  year={2016},
  volume={79},
  pages={427-436}
}
Mitochondria are the powerhouses for the cell, consuming oxygen to generate sufficient energy for the maintenance of normal cellular processes. However, a deleterious consequence of this process are reactive oxygen species generated as side-products of these reactions. As a means to protect mitochondria from damage, cells and mitochondria have developed a wide-range of mitochondrial quality control mechanisms that remove damaged mitochondrial cargo, enabling the mitochondria to repair the… CONTINUE READING