Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

@article{Nagasawa1996DefectsOB,
  title={Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1},
  author={Takashi Nagasawa and Seiichi Hirota and Kazunobu Tachibana and Nobuyuki Takakura and Shin-ichi Nishikawa and Yukihiko Kitamura and Nobuaki Yoshida and Hitoshi Kikutani and Tadamitsu Kishimoto},
  journal={Nature},
  year={1996},
  volume={382},
  pages={635-638}
}
THE chemokines are a large family of small, structurally related cytokines1,2. The physiological importance of most members of this family has yet to be elucidated, although some are inducible inflammatory mediators that determine leukocyte chemotaxis1–5. Pre-B-cell growth-stimulating factor/stromal cell-derived factor-1 (PBSF/SDF-1) is a member of the CXC group of chemokines6,7. PBSF/SDF-1 stimulates proliferation of B-cell progenitors in vitro6 and is constitutively expressed in bone-marrow… CONTINUE READING
Highly Influential
This paper has highly influenced 25 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 854 extracted citations

Similar Papers

Loading similar papers…