Defective p56Lck activity in T cells from an adult patient with idiopathic CD4+ lymphocytopenia.

@article{Hubert2000DefectivePA,
  title={Defective p56Lck activity in T cells from an adult patient with idiopathic CD4+ lymphocytopenia.},
  author={Pascale Hubert and Francis Bergeron and Val{\'e}rie Ferreira and Maxime Seligmann and Eric Oksenhendler and Patrice Debr{\'e} and Brigitte Autran},
  journal={International immunology},
  year={2000},
  volume={12 4},
  pages={449-57}
}
Idiopathic CD4(+) lymphocytopenia (ICL) is defined by a stable loss of CD4(+) T cells in the absence of any known cause of immune deficiency. This syndrome is still of undetermined origin. It affects adult patients, some of them displaying opportunistic infections similar to HIV-infected subjects. The hypothesis that the cellular immune defect may be due to… CONTINUE READING