Defective neutrophil chemotactic responses in patients with recurrent episodes of otitis media and chronic diarrhea.


Fourteen patients who had repeated episodes of otitis media and diarrhea were evaluated to determine if a defect in the host defense mechanism could account for the unusual incidence of infection. Each of the patients with recurrent otitis media and diarrhea had a profound defect in neutrophil chemotactic responsiveness. The mean chemotactic index of the… (More)


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