Defective monocyte chemotaxis in patients with head and neck cancer. Restoration after treatment.

@article{Tan1986DefectiveMC,
  title={Defective monocyte chemotaxis in patients with head and neck cancer. Restoration after treatment.},
  author={Ing Bing Tan and Hemmo A. Drexhage and Rik J. Scheper and B Mary E von Blomberg-van der Flier and Meeny de Haan-Meulman and Gordon B J Snow and Alfons J. M. Balm},
  journal={Archives of otolaryngology--head & neck surgery},
  year={1986},
  volume={112 5},
  pages={541-4}
}
Monocyte chemotactic responsiveness (MCR), as measured by the monocytes' capacity to migrate through polymer (Millipore) membranes toward the chemoattractant casein, is impaired in all patients with head and neck cancer thus far examined. Using a more rapid and sensitive test system, the polarization assay, we tested the MCR in 24 patients with head and neck cancer and 31 controls and compared it with the outcomes of the well-established Boyden chamber method. The results of both methods… CONTINUE READING