Defective annexin A5 crystallization: a mechanism for pregnancy losses in the antiphospholipid syndrome.

@article{Rand2005DefectiveAA,
  title={Defective annexin A5 crystallization: a mechanism for pregnancy losses in the antiphospholipid syndrome.},
  author={Jacob H. Rand and P. A. van der Eerden and Xiao Xiong Wu and Cynthia Chazotte},
  journal={Thrombosis research},
  year={2005},
  volume={115 Suppl 1},
  pages={
          77-81
        }
}
We have accumulated a significant body of evidence that support the hypothesis that aPL antibody-mediated disruption of annexin A5 crystallization is a mechanism for RSPL in the APS. Further investigation of the functions of the annexins in placental physiology and disease are likely to be productive areas for future research.