Defective DNA mismatch repair in acute myeloid leukemia/myelodysplastic syndrome after organ transplantation.

@article{Offman2004DefectiveDM,
  title={Defective DNA mismatch repair in acute myeloid leukemia/myelodysplastic syndrome after organ transplantation.},
  author={Judith Offman and Gerhard Opelz and Bernd D{\"o}hler and David Cummins and Ozay Halil and Nicholas Robert Banner and Margaret M. Burke and Dianne C Sullivan and Peter Macpherson and P. Karran},
  journal={Blood},
  year={2004},
  volume={104 3},
  pages={822-8}
}
Immunosuppression after organ transplantation is an acknowledged risk factor for skin cancer and lymphoma. We examined whether there was also an excess of leukemia in patients after transplantation and whether this might be related to a particular immunosuppressive treatment. Data from more than 170 000 patients indicated that organ transplantation is associated with a significantly increased risk for acute myeloid leukemia (AML). AML was more frequent after heart transplantation and lung… CONTINUE READING
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