Defect in an intrahepatic degradation of apolipoprotein B in suncus: an animal model of hypobetalipoproteinemia.

Abstract

We have previously shown that fatty liver is easily induced in suncus by starvation and that the plasma level of apolipoprotein B (apo B) is very low. We also found that hepatic acyl coenzyme A cholesterol acyltransferase (ACAT) activity is almost absent in the animals, resulting in decreased cholesteryl ester contents in the liver. A deficiency of… (More)

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Cite this paper

@article{Liang1998DefectIA, title={Defect in an intrahepatic degradation of apolipoprotein B in suncus: an animal model of hypobetalipoproteinemia.}, author={Y Q Liang and Minako Kinoshita and T. Muto and Yuko Fujimaki and Naoto Matsuki and H. Saito and M. Yamanaka and Takahide Teramoto}, journal={Journal of biochemistry}, year={1998}, volume={123 1}, pages={28-32} }