Defect in Synaptic Vesicle Precursor Transport and Neuronal Cell Death in KIF1A Motor Protein–deficient Mice

@article{Yonekawa1998DefectIS,
  title={Defect in Synaptic Vesicle Precursor Transport and Neuronal Cell Death in KIF1A Motor Protein–deficient Mice },
  author={Yoshiaki Yonekawa and Akihiro Harada and Yasushi Okada and Takeshi Funakoshi and Yoshimitsu Kanai and Yosuke Takei and Sumio Terada and Tetsuo Noda and Nobutaka Hirokawa},
  journal={The Journal of Cell Biology},
  year={1998},
  volume={141},
  pages={431 - 441}
}
The nerve axon is a good model system for studying the molecular mechanism of organelle transport in cells. Recently, the new kinesin superfamily proteins (KIFs) have been identified as candidate motor proteins involved in organelle transport. Among them KIF1A, a murine homologue of unc-104 gene of Caenorhabditis elegans, is a unique monomeric neuron- specific microtubule plus end-directed motor and has been proposed as a transporter of synaptic vesicle precursors (Okada, Y., H. Yamazaki, Y… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 120 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 41 references

The C

  • A. J. Otsuka, A. Jeyaprakash, +5 authors T. Born.
  • elegans unc-104 gene encodes a putative kinesin…
  • 1991
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…