Default-mode and task-positive network activity in major depressive disorder: implications for adaptive and maladaptive rumination.

Abstract

BACKGROUND Major depressive disorder (MDD) has been associated reliably with ruminative responding; this kind of responding is composed of both maladaptive and adaptive components. Levels of activity in the default-mode network (DMN) relative to the task-positive network (TPN), as well as activity in structures that influence DMN and TPN functioning, may… (More)
DOI: 10.1016/j.biopsych.2011.02.003

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