Deep vein thrombosis and pulmonary embolism

  title={Deep vein thrombosis and pulmonary embolism},
  author={Marcello Di Nisio and Nick van Es and Harry R B{\"u}ller},
  journal={The Lancet},
Deep Venous Thrombosis and Pulmonary Embolism
This chapter reviews the diagnosis of PE and DVT including different testing modalities, and different therapies are discussed such as thrombolytics, anticoagulation, and prevention of venous thrombosis.
Deep Venous Thrombosis and Venous Thromboembolism Prevention in the Neurocritical Care Unit
The available evidence supports the use of mechanical and chemical VTE prophylaxis as beneficial in reducing the risk of developing DVT and PE; unfortunately, therisk of hemorrhagic complications when starting chemical prophYLaxis remains a substantial concern for health-care providers.
Venous Thromboembolism: Role of the Clinical Laboratory in Diagnosis and Management.
BACKGROUND Venous thromboembolism (VTE) is the third most common cause of cardiovascular illness and is projected to double in incidence by 2050. It is a spectrum of disease that includes deep venous
Development and validation of a prediction model to estimate risk of acute pulmonary embolism in deep vein thrombosis patients
A novel prediction model is developed to identify patients with different risks for APE in DVT patients, which may be useful for quickly estimating the probability of APE before obtaining definitive test results and speeding up emergency management processes.
Travel as a risk factor for venous thromboembolic disease.
There is evidence that the incidence of travel-related pulmonary embolism appears to be related to the distance travelled and immobility during the flights, and the use of below-knee graduated compression stockings seems to be highly effective.
Advanced Therapies for Acute Pulmonary Embolism: A Focus on Catheter-Based Therapies and Future Directions
Emerging strategies utilizing adjunctive mechanical circulatory support may improve outcomes in the highest risk patients, providing stabilization prior to definitive therapy and potentially obviating the need for invasive measures.
Neurologic complications of venous thromboembolism.
  • M. Schneck
  • Medicine
    Handbook of clinical neurology
  • 2021


The Role of Venous Ultrasonography in the Diagnosis of Suspected Deep Venous Thrombosis and Pulmonary Embolism
The strengths and weaknesses of venous ultrasonography are considered in patients with the five clinical presentations of suspected venous thromboembolism and the criteria used to diagnose thrombosis often vary among examiners.
Natural History of Venous Thromboembolism
After a course of treatment, the risk of recurrent thrombosis is higher in patients without reversible risk factors, in patients with cancer, and in those with prothrombotic biochemical abnormalities such as antiphospholipid antibodies and homozygous factor V Leiden.
Meta-Analysis: Outcomes in Patients with Suspected Pulmonary Embolism Managed with Computed Tomographic Pulmonary Angiography
A systematic review of the literature and meta-analysis of eligible studies to determine the safety and efficacy of withholding systemic anticoagulation after negative results on spiral computed tomographic pulmonary angiography (CTPA).
D-dimer to guide the duration of anticoagulation in patients with venous thromboembolism: a management study.
Serial D-dimer measurement is suitable in clinical practice for the identification of VTE patients in whom anticoagulation can be safely discontinued, and can identify subjects at low recurrence risk.
The diagnosis of symptomatic recurrent pulmonary embolism and deep vein thrombosis: guidance from the SSC of the ISTH
This document is intended to give clinical guidance for the diagnosis of symptomatic recurrent pulmonary embolism (PE) and/or deep vein thrombosis (DVT). We define recurrent PE and DVT as those
Treatment of venous thromboembolism.
The mainstay of VTE treatment is anticoagulation, while interventions such as thrombolysis and inferior vena cava filters are reserved for limited circumstances and better prediction tools for major hemorrhage are needed.
Evaluation of D-dimer in the diagnosis of suspected deep-vein thrombosis.
Deep-vein thrombosis can be ruled out in a patient who is judged clinically unlikely to have deep-veIn thromBosis and who has a negative D-dimer test, and ultrasound testing can be safely omitted in such patients.
Does this patient have deep vein thrombosis?
D diagnostic accuracy for DVT improves when clinical probability is estimated before diagnostic tests, and studies involving more than 8000 patients used 1 clinical prediction rule for diagnosing DVT, of which 11 incorporated D-dimer testing in the diagnostic algorithm.
Risk Assessment of Recurrence in Patients With Unprovoked Deep Vein Thrombosis or Pulmonary Embolism: The Vienna Prediction Model
By use of a simple scoring system, the assessment of the recurrence risk in patients with a first unprovoked VTE and without strong thrombophilic defects can be improved.