Deep brain stimulation suppresses pallidal low frequency activity in patients with phasic dystonic movements.

@article{Barow2014DeepBS,
  title={Deep brain stimulation suppresses pallidal low frequency activity in patients with phasic dystonic movements.},
  author={Ewgenia Barow and Wolf-Julian Neumann and Christof Br{\"u}cke and Julius Huebl and Andreas Horn and Peter Brown and Joachim K. Krauss and Gerd-Helge Schneider and Andrea A. K{\"u}hn},
  journal={Brain : a journal of neurology},
  year={2014},
  volume={137 Pt 11},
  pages={3012-3024}
}
Deep brain stimulation of the globus pallidus internus alleviates involuntary movements in patients with dystonia. However, the mechanism is still not entirely understood. One hypothesis is that deep brain stimulation suppresses abnormally enhanced synchronized oscillatory activity within the motor cortico-basal ganglia network. Here, we explore deep brain stimulation-induced modulation of pathological low frequency (4-12 Hz) pallidal activity that has been described in local field potential… CONTINUE READING

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