Deep brain stimulation results in local glutamate and adenosine release: investigation into the role of astrocytes.

@article{Tawfik2010DeepBS,
  title={Deep brain stimulation results in local glutamate and adenosine release: investigation into the role of astrocytes.},
  author={Vivianne L. Tawfik and Su-Youne Chang and Frederick L. Hitti and David W. Roberts and James C Leiter and Svetlana Jovanovic and Kendall H. Lee},
  journal={Neurosurgery},
  year={2010},
  volume={67 2},
  pages={367-75}
}
BACKGROUND Several neurological disorders are treated with deep brain stimulation; however, the mechanism underlying its ability to abolish oscillatory phenomena associated with diseases as diverse as Parkinson's disease and epilepsy remain largely unknown. OBJECTIVE To investigate the role of specific neurotransmitters in deep brain stimulation and determine the role of non-neuronal cells in its mechanism of action. METHODS We used the ferret thalamic slice preparation in vitro, which… CONTINUE READING

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Deep brain stimulation of the ventral capsule/ ventral striatum for treatment-resistant depression

  • DA JrMalone, DD Dougherty, AR Rezai
  • Biol Psychiatry Feb
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