Deep brain stimulation for treatment-resistant depression: efficacy, safety and mechanisms of action.

Abstract

Deep brain stimulation (DBS), a neuromodulation therapy that has been used successfully in the treatment of symptoms associated with movement disorders, has recently undergone clinical trials for individuals suffering from treatment-resistant depression (TRD). Although the small patient numbers and open label study design limit our ability to identify… (More)
DOI: 10.1016/j.neubiorev.2012.06.001

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