Deep brain stimulation for psychiatric disease: contributions and validity of animal models.

@article{Hamani2012DeepBS,
  title={Deep brain stimulation for psychiatric disease: contributions and validity of animal models.},
  author={Clement Hamani and Yasin Temel},
  journal={Science translational medicine},
  year={2012},
  volume={4 142},
  pages={142rv8}
}
During treatment with deep brain stimulation (DBS), electrical current is delivered into the brain parenchyma through implanted electrodes. Although this technique is routinely used in the treatment of Parkinson's disease, essential tremor, and dystonia, a growing number of neuropsychiatric applications for DBS are being investigated. Investigators can use animal models of these diseases to study the mechanisms through which DBS exerts its effects, to explore new applications of this therapy… CONTINUE READING
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Effects of electrical stimulation or lesion in nucleus accumbens on the behaviour of rats in a T-maze after administration of 8-OH-DPAT or vehicle

  • K. van Kuyck, H. Demeulemeester, +8 authors B. Nuttin
  • Behav. Brain Res
  • 2003
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