Deep brain stimulation for obsessive–compulsive disorders: long-term analysis of quality of life

  title={Deep brain stimulation for obsessive–compulsive disorders: long-term analysis of quality of life},
  author={Pieter Ooms and Mariska Mantione and Martijn Figee and P. Richard Schuurman and Pepijn van den Munckhof and Damiaan A.J.P. Denys},
  journal={Journal of Neurology, Neurosurgery \& Psychiatry},
  pages={153 - 158}
Objective To evaluate the long-term effects of deep brain stimulation (DBS) on quality of life (QOL) in therapy-refractory obsessive–compulsive disorder (OCD) patients. Design 16 patients who met Diagnostic and Statistical Manual of Mental Disorders (4th ed) (DSM-IV) criteria for OCD and were considered therapy-refractory were treated with DBS. Patients were assessed 1 month before device implantation (T0), at 8 months of active stimulation (T1) and at 3–5 years of active stimulation (T2). QOL… 

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Bilateral deep brain stimulation of the nucleus accumbens may be an effective and safe treatment for treatment-refractory OCD and no permanent adverse events were reported.

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DBS may be a promising and safe therapy for treatment-resistant OCD and larger prospective studies including neuroimaging are needed to estimate adequately the true potential in treatment of OCD.

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