Deep brain stimulation for chronic pain investigated with magnetoencephalography

@article{Kringelbach2007DeepBS,
  title={Deep brain stimulation for chronic pain investigated with magnetoencephalography},
  author={Morten L. Kringelbach and Ned Jenkinson and Alexander L. Green and Sarah L. F. Owen and Peter C. Hansen and Piers L. Cornelissen and Ian E. Holliday and John F. Stein and Tipu Z. Aziz},
  journal={NeuroReport},
  year={2007},
  volume={18},
  pages={223-228}
}
Deep brain stimulation has shown remarkable potential in alleviating otherwise treatment-resistant chronic pain, but little is currently known about the underlying neural mechanisms. Here for the first time, we used noninvasive neuroimaging by magnetoencephalography to map changes in neural activity induced by deep brain stimulation in a patient with severe phantom limb pain. When the stimulator was turned off, the patient reported significant increases in subjective pain. Corresponding… 
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