Deep brain stimulation for chronic pain investigated with magnetoencephalography

@article{Kringelbach2007DeepBS,
  title={Deep brain stimulation for chronic pain investigated with magnetoencephalography},
  author={Morten L. Kringelbach and Ned Jenkinson and Alexander L. Green and Sarah L. F. Owen and Peter C. Hansen and Piers L. Cornelissen and Ian E. Holliday and John F. Stein and Tipu Z. Aziz},
  journal={NeuroReport},
  year={2007},
  volume={18},
  pages={223-228}
}
Deep brain stimulation has shown remarkable potential in alleviating otherwise treatment-resistant chronic pain, but little is currently known about the underlying neural mechanisms. Here for the first time, we used noninvasive neuroimaging by magnetoencephalography to map changes in neural activity induced by deep brain stimulation in a patient with severe phantom limb pain. When the stimulator was turned off, the patient reported significant increases in subjective pain. Corresponding… Expand
Deep brain stimulation for chronic pain
Deep brain stimulation (DBS) is a neurosurgical intervention popularised in movement disorders such as Parkinson's disease, and also reported to improve symptoms of epilepsy, Tourette's syndrome,Expand
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MEG Can Map Short and Long-Term Changes in Brain Activity following Deep Brain Stimulation for Chronic Pain
TLDR
An analysis of magnetoencephalography data from a patient with whole-body chronic pain finds significant changes in activity in pain-related regions including the pre-supplementary motor area, brainstem, and dissociable parts of caudal and rostral ACC. Expand
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TLDR
DBS of the ventral capsule was employed to modulate the affective component of pain and thereby reduce pain related disability in PSTP and departure from conventional approach. Expand
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TLDR
Deep brain stimulation of the ventral posterior thalamus, periventricular/periaqueductal gray matter, and latterly rostral anterior cingulate cortex (Cg24) in 113 patients treated at 2 centers over 13 years is summarized. Expand
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The results show that MEG can be used to measure brain activity regardless of the presence of high frequency deep brain stimulation. Expand
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In conclusion, affective ACC DBS can relieve chronic neuropathic pain refractory to pharmacotherapy and restore quality of life. Expand
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