Deep brain stimulation can suppress pathological synchronisation in parkinsonian patients

Abstract

BACKGROUND Although deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a highly effective therapeutic intervention in severe Parkinson's disease, its mechanism of action remains unclear. One possibility is that DBS suppresses local pathologically synchronised oscillatory activity. METHODS To explore this, the authors recorded from DBS… (More)
DOI: 10.1136/jnnp.2010.217489

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