Deep brain stimulation and climbing fiber synaptic pathology in essential tremor.

Abstract

Essential tremor (ET) patients have abnormal climbing fiber (CF) synapses in the parallel fiber territory in the cerebellum, and these abnormal CF synapses are inversely correlated with tremor severity. We therefore examined CF synaptic pathology in ET cases with and without thalamic deep brain stimulation (DBS) and assessed the association with tremor… (More)
DOI: 10.1002/ana.24728

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