Deep Brain Stimulation for Dystonia in Adults

@article{Krauss2002DeepBS,
  title={Deep Brain Stimulation for Dystonia in Adults},
  author={Joachim K. Krauss},
  journal={Stereotactic and Functional Neurosurgery},
  year={2002},
  volume={78},
  pages={168 - 182}
}
  • J. Krauss
  • Published 2002
  • Medicine
  • Stereotactic and Functional Neurosurgery
The renaissance of functional neurosurgery in the treatment of Parkinson’s disease has sparked also the interest in other movement disorders which are refractory to medical treatment. Deep brain stimulation (DBS) has been used only since a few years in dystonia patients. This review summarizes the available data on pallidal and thalamic DBS for various dystonic syndromes. The major advantage of DBS as compared to radiofrequency lesioning is that it allows performing contemporaneous bilateral… Expand
Neuromodulation in Dystonia: Current Aspects of Deep Brain Stimulation
  • H. Capelle, J. Krauss
  • Medicine
  • Neuromodulation : journal of the International Neuromodulation Society
  • 2009
TLDR
An account on the development of surgical neuromodulation therapy for dystonia, surgical approaches, hardware‐related problems, DBS programming and patient management, and clinical outcome, and the implications of intra‐operative microelectrode recordings and pallidal field potentials for the pathophysiology of dySTONia are discussed. Expand
The Physiological Effects of Pallidal Deep Brain Stimulation in Dystonia
TLDR
Physiological and imaging studies in dystonia patients with GPi DBS suggest that deep brain stimulation (DBS) of globus pallidus internus (GPi) acts primarily by major modification of basal ganglia output to brainstem, thalamus, and cortex resulting in neural reorganization, which may explain the characteristic progressive improvement in dySTONia after GPu DBS. Expand
Deep Brain Stimulation in Dystonia
Accumulating and more controlled data is providing strong evidence that bilateral pallidal deep brain stimulation (DBS) produces a marked beneficial effect in dystonia severity and disability inExpand
Deep brain stimulation for dystonia
TLDR
The issues related to DBS treatment of dystonia are reviewed, including proper patient selection, surgical approaches to target choice and device implant, a description of the stimulating device and its programming principles, clinical results – with a focus on different outcomes for primary versus secondary and generalized versus cervical dySTONia – and complications. Expand
Deep brain stimulation of globus pallidus internus for dystonia.
TLDR
In comparison to the effects seen in PD, the improvement in dystonic postures appear to differ in several ways--delay of clinical benefit, higher voltage requirements, and varied stimulator settings. Expand
Bilateral deep-brain stimulation of the globus pallidus in primary generalized dystonia.
TLDR
These findings support the efficacy and safety of the use of bilateral stimulation of the internal globus pallidus in selected patients with primary generalized dystonia. Expand
Deep brain stimulation for pediatric movement disorders.
TLDR
The role of DBS is reviewed and the experience with establishing a dedicated pediatric DBS program is reviewed, with only a few experienced centers worldwide. Expand
Pallidal Deep Brain Stimulation for a Case of Hemidystonia Secondary to a Striatal Stroke
TLDR
The patient had marked benefit from bilateral GPi DBS, which suggests that the therapeutic effects of DBS were mediated by the intact pathways in this case of hemidystonia. Expand
Deep brain stimulation for movement disorders before DBS for movement disorders.
TLDR
This paper reviews the gestational pre-natal era of deep brain stimulation, before 1987, and credits the Grenoble Group to have reinvented, modernised and expanded modern DBS in surgical treatment of movement disorders. Expand
Deep Brain Stimulation for Status Dystonicus: A Case Series and Review of the Literature
TLDR
DBS is an effective therapeutic modality for the treatment of SD and early and aggressive treatment may improve the overall outcome, in addition to the long-term benefits of stimulation. Expand
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TLDR
Although this is a retrospective study dealing with dystonia of heterogeneous etiology, the results strongly suggest that GPi DBS has a better outcome than VLp DBS. Expand
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Deep Brain Stimulation of the Globus Pallidus internus is an alternative approach for severe cases of generalized dystonia and first improvement of symptoms was observed after surgery. Expand
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TLDR
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TLDR
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TLDR
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