Deep Brain Stimulation

@article{Chen2012DeepBS,
  title={Deep Brain Stimulation},
  author={X. L. Chen and Y. Xiong and G. L. Xu and X. Liu},
  journal={Interventional Neurology},
  year={2012},
  volume={1},
  pages={200 - 212}
}
Deep brain stimulation (DBS) has provided remarkable therapeutic benefits for people with a variety of neurological disorders. Despite the uncertainty of the precise mechanisms underlying its efficacy, DBS is clinically effective in improving motor function of essential tremor, Parkinson's disease and primary dystonia and in relieving obsessive-compulsive disorder. Recently, this surgical technique has continued to expand to other numerous neurological diseases with encouraging results. This… Expand
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Deep brain stimulation has largely replaced ablative procedures for the treatment of advanced Parkinson disease, essential tremor, and dystonia. It is also approved for obsessive-compulsive disorder.Expand
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The patient population most likely to benefit from surgery, what aspects of the disease are most responsive, the current limitations of DBS, and new therapeutic targets that are being examined to address these limitations are discussed. Expand
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This review addresses the main hypotheses on the mechanisms of action of DBS and concludes that stimulation-induced desynchronization of network oscillations represents the hypothesis that best explains the presently available data. Expand
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