Dectin-1 and inflammation-associated gene transcription and expression in mouse lungs by a toxic (1,3)-β-d glucan

@article{Rand2009Dectin1AI,
  title={Dectin-1 and inflammation-associated gene transcription and expression in mouse lungs by a toxic (1,3)-β-d glucan},
  author={Thomas. G. Rand and Ming Sun and Andrew Gilyan and Jordan Downey and Joseph D. Miller},
  journal={Archives of Toxicology},
  year={2009},
  volume={84},
  pages={205-220}
}
The form of (1-3)-β-d glucan found in the cell walls of the anamorphic Trichocomaceae that grow on damp building materials is considered to have potent toxic and inflammatory effects on cells of the respiratory system. It is also considered to have a potential role in the development of non-allergenic respiratory health effects. While human studies involving experimental exposures all point to the inflammatory potential of pure curdlan, a linear (1-3)-β-d glucan in a triple helix configuration… CONTINUE READING

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