Decreasing rate of multiple treatment modifications among individuals who initiated antiretroviral therapy in 1997-2009 in the Danish HIV Cohort Study.

@article{Helleberg2012DecreasingRO,
  title={Decreasing rate of multiple treatment modifications among individuals who initiated antiretroviral therapy in 1997-2009 in the Danish HIV Cohort Study.},
  author={Marie Helleberg and Gitte Kronborg and Carsten Schade Larsen and Gitte Pommergaard Pedersen and C. Korsg{\aa}rd Pedersen and Lars Kjaer Nielsen and A. L. Laursen and Niels Obel and Jan Gerstoft},
  journal={Antiviral therapy},
  year={2012},
  volume={18 3},
  pages={
          345-354
        }
}
BACKGROUND We hypothesized that rates and reasons for treatment modifications have changed since the implementation of combination antiretroviral therapy (cART) due to improvements in therapy. METHODS From a nationwide population-based cohort study we identified all HIV-1-infected adults who initiated cART in Denmark 1997-2009 and were followed ≥1 year. Incidence rate ratios (IRRs) and reasons for treatment modifications were estimated and compared between patients, who initiated treatment in… CONTINUE READING

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