Decreasing mitochondrial fission diminishes vascular smooth muscle cell migration and ameliorates intimal hyperplasia.

@article{Wang2015DecreasingMF,
  title={Decreasing mitochondrial fission diminishes vascular smooth muscle cell migration and ameliorates intimal hyperplasia.},
  author={Li Wang and Tianzheng Yu and Hakjoo Lee and Dawn K O'Brien and Hiromi Sesaki and Yisang Yoon},
  journal={Cardiovascular research},
  year={2015},
  volume={106 2},
  pages={272-83}
}
AIMS Vascular smooth muscle cell (VSMC) migration in response to arterial wall injury is a critical process in the development of intimal hyperplasia. Cell migration is an energy-demanding process that is predicted to require mitochondrial function. Mitochondria are morphologically dynamic, undergoing continuous shape change through fission and fusion. However, the role of mitochondrial morphology in VSMC migration is not well understood. The aim of the study is to understand how mitochondrial… CONTINUE READING
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