Decreasing choline signal—a marker of phenylketonuria?

Abstract

We found a statistically significant increase in theN-acetylaspartate/choline-containing compounds (NAA/Cho) ratio in a group of 69 phenylketonuria (PKU) patients with a rise in echo time (TE) compared with a group of 35 age-matched controls. The absolute concentration of creatine did not differ significantly between patients and controls, but a significant… (More)
DOI: 10.1007/BF01772005

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