Decreased volume of left and total anterior insular lobule in schizophrenia.

  title={Decreased volume of left and total anterior insular lobule in schizophrenia.},
  author={Nikos Makris and Jill M. Goldstein and David N. Kennedy and Steven M. Hodge and Verne S. Caviness and Stephen V Faraone and Ming T. Tsuang and Larry J. Seidman},
  journal={Schizophrenia research},
  volume={83 2-3},
The insula is anatomically situated to be critically involved in many bio-behavioral functions impaired in schizophrenia. Furthermore, its total volume has been shown to be reduced in schizophrenia. In the present study, we tested the hypothesis that in schizophrenia it is the anterior insular lobule (aINS(lbl)) rather than the posterior insular lobule (pINS(lbl)) that is smaller, given that limbic system abnormalities are central in schizophrenia and that the affiliations of the limbic system… CONTINUE READING
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