Decreased thymosin beta4 in apoptosis induced by a variety of antitumor drugs.

@article{Iguchi1999DecreasedTB,
  title={Decreased thymosin beta4 in apoptosis induced by a variety of antitumor drugs.},
  author={Kazuhiro Iguchi and Yu Usami and Kazuyuki Hirano and Motoharu Hamatake and Masa-Aki Shibata and Ryoji Ishida},
  journal={Biochemical pharmacology},
  year={1999},
  volume={57 10},
  pages={1105-11}
}
As many antitumor drugs can kill tumors through the induction of apoptosis, the effect of these drugs presumably would be enhanced if they were used in combination with other drugs that interact with apoptotic processes. To clarify the biological events involved in the induction of apoptosis, we examined changes in the proteins associated with induction of apoptosis by antitumor drugs. When Molt-4 cells were exposed to the antitumor drugs etoposide, meso-2,3-bis(3,5-dioxopiperazine-1-yl)butane… CONTINUE READING

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