Decreased striatal dopamine transporter binding in a patient with extrapontine myelinolysis.

@article{Kim2003DecreasedSD,
  title={Decreased striatal dopamine transporter binding in a patient with extrapontine myelinolysis.},
  author={Joong Seok Kim and Kwangsoo Lee and Si-Ryung Han and Yong-An Chung},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2003},
  volume={18 3},
  pages={
          342-5
        }
}
We describe the case of a 61-year-old woman who developed extrapontine myelinolysis (EPM) with parkinsonism. Decreased striatal dopamine transporter binding assessed by [(123)I]N-(3-iodopropen-2-yl)-2beta-carbomethoxy-3beta-(4-chlorophenyl) tropane and single photon emission computed tomography ([(123)I]IPT) SPECT) were observed in the patient, suggesting that osmotic injury causes the demyelination of nigrostriatal dopaminergic neurons and that such injury may be involved in the pathogenesis… CONTINUE READING
BETA