Decreased sialidase activity in mononuclear leucocytes of type 1 diabetic subjects: relationship to diabetic complications and glycaemic control.

Abstract

Leucocyte surface sialic acid content influences surface charge, deformability, and leucocyte-endothelial interaction. Abnormal leucocyte structure and function contributes both to microvascular damage and diabetic complications. The aim of this study was to investigate altered leucocyte SA metabolism in diabetic subjects and measure lysosomal sialidase… (More)

Topics

Cite this paper

@article{Waters1995DecreasedSA, title={Decreased sialidase activity in mononuclear leucocytes of type 1 diabetic subjects: relationship to diabetic complications and glycaemic control.}, author={Paula J. Waters and Mark Flynn and Charles Pennock and Roger J M Corrall and Ronni Greenwood and Robert Eisenthal}, journal={Diabetic medicine : a journal of the British Diabetic Association}, year={1995}, volume={12 8}, pages={670-3} }