Decreased serum levels of platelet-endothelial adhesion molecule (PECAM-1) in subjects with high-functioning autism: a negative correlation with head circumference at birth.

@article{Tsuchiya2007DecreasedSL,
  title={Decreased serum levels of platelet-endothelial adhesion molecule (PECAM-1) in subjects with high-functioning autism: a negative correlation with head circumference at birth.},
  author={Kenji Tsuchiya and Kenji Hashimoto and Yasuhide Iwata and Masatsugu Tsujii and Yoshimoto Sekine and Genichi Sugihara and Hideo Matsuzaki and Shiro Suda and Masayoshi Kawai and Kazuhiko Nakamura and Yoshio Minabe and Atsuko Yagi and Masaomi Iyo and Nori Takei and Norio Mori},
  journal={Biological psychiatry},
  year={2007},
  volume={62 9},
  pages={1056-8}
}
BACKGROUND Accumulating evidence suggests that the immune system plays a role in the pathophysiology of autism, and that the adhesion molecules play an important role in the process of inflammation. This study was undertaken to determine whether serum levels of the adhesion molecules in subjects with high-functioning autism are altered as compared with those of normal controls. METHODS Seventeen male subjects with high-functioning autism and 22 male age-matched unrelated healthy control… CONTINUE READING